Determination of some biochemical markers and antioxidants in patients with renal diseases
Keywords:
Renal Diseases, Oxidative Stress, Nitric Oxide, Catalase, Kidney FunctionAbstract
A study was conducted to determine and evaluate the level of some biochemical variables in people with kidney disease compared to healthy people as a control sample. It was observed that the level of kidney function increased in terms of urea, uric acid, and creatine as a result of the decreased efficiency of the kidneys in filtration. While the level of total protein and albumin in the blood serum decreased as a result of their loss through the urine, while an increase in blood globulins was observed in infected male and female patients as a result of the immune response. Kidney disease may cause the development of oxidative stress, which was clearly demonstrated by the level of nitric oxide, which is a true measure of the occurrence of oxidative stress, and a decrease was found. In the most important antioxidant criteria measured for people with kidney disease, there was a decrease in the effectiveness of SOD, CAT enzyme, and ceruloplasmin, which confirms the depletion of these antioxidants to defend against damage oxidative stress formed as a result of kidney disease.
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