Seroepidemiology of Parvovirus B19 (PVB19] and Human Papillomavirus [HPV] 16 and 18 in Women with Abnormal Pregnancy Outcomes: A Review

Parvovirus B19 and HPV

Abstract

Background: The role of Parvovirus B 19 (PVB19) and human papillomavirus (HPV) was not fully understood as there is a limited study that reported the seroepidemiology of these agents.
Aim: To evaluate the role of PVB19 and HPV 16 and 18 as risk factor on pregnancy outcomes
Materials and methods: Published articles on the role of PVB19, HPV 16 and 18 in women with bad obstetrics history retrieved from Google and reviewed. For PVB19 thirty-five global studies and 9 studies in Arab countries were reviewed.
Results: PVB19 median for IgG seroprevalence was 53.3%, while for IgM the median seroprevalence was 10.3%. Additionally, the mean IgG seroprevalence was 53.04±23.6%, while IgM mean seroprevalence was 20.01±27.71%. HPV seroprevalence of HPV-16 was with a range of 0.72% to 97.71%, while, HPV-18 seroprevalence was with a range of 0.5% to 27.6%.
Conclusions: HPV and PVB 19 were with a wide range of seroprevalence, however, may play a role in the development of bad obstetric outcome