Evaluation of the level of the immunoglobulin Hepcidin and Interleukin-6 in the blood serum of patients infected with Covid-19 virus

Abstract

The current study included 90 samples, 60 samples were infected with the emerging corona virus and 30 samples were a control group (healthy) without any disease and their ages ranged between (40-75) years and the samples were collected from Baquba General Teaching Hospital in Diyala Governorate, then blood was collected from healthy and sick people  It was separated by a centrifuge, and the level of ferritin, hepcidin and interleukin-6 was measured, as well as the level of C-reactive protein-CRP, and the D-dimer for the purpose of diagnosis or confirmation of infection with the emerging corona virus.  The results of the current research showed a significant increase (P≤ 0.05) in the level of C-reactive protein as it was (55.062 ± 14.979) mg / l in patients infected with Covid-19, while the control group (healthy people) was (5.520 ± 0.784) mg / l  And a significant increase (P≤ 0.05) in the level of the dimer, which was (540.181 ± 39.830) ng/ml in patients infected with Covid-19, while the control group (healthy people) was (210.56 ± 58.594) ng/ml.  A significant increase (P≤ 0.05) in ferritin level was (683.17 ± 74.982) ng/ml in patients infected with Covid-19, while the control group (healthy people) was (107.563 ± 39.372) ng/ml.  And a significant increase (P≤ 0.05) in the level of hepcidin, as it was (46.53009 ± 20.634726) pg/ml in patients infected with covid-19, while it was (6.15967 ± 2.022133) pg/ml in a group of healthy people as a control group.  P≤ 0.05) in the concentration of interleukin-6, as it was (14.74640 ± 3.112274) pg/ml in patients with covid-19, while it was (3.96352 ± 1.261544) pg/ml in healthy people as a control group.